The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Oct. 18, 2013
Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Kenji Otsubo, Osaka, JP;

Takahito Yamauchi, Osaka, JP;

Yuji Ochi, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/04 (2006.01); C07D 221/06 (2006.01); C07D 215/22 (2006.01); C07D 215/26 (2006.01); C07D 215/28 (2006.01); C07D 215/40 (2006.01); C07D 215/48 (2006.01); C07D 221/10 (2006.01); C07D 221/16 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 491/04 (2006.01); C07F 9/60 (2006.01); C07F 9/6558 (2006.01); C07F 9/6561 (2006.01); C07H 19/04 (2006.01); C07D 215/233 (2006.01); C07D 215/18 (2006.01);
U.S. Cl.
CPC ...
C07D 221/06 (2013.01); C07D 215/22 (2013.01); C07D 215/26 (2013.01); C07D 215/28 (2013.01); C07D 215/40 (2013.01); C07D 215/48 (2013.01); C07D 221/10 (2013.01); C07D 221/16 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 491/04 (2013.01); C07F 9/60 (2013.01); C07F 9/65583 (2013.01); C07F 9/6561 (2013.01); C07H 19/04 (2013.01); C07D 215/233 (2013.01); C07D 215/18 (2013.01);
Abstract

The present invention provides a quinolone compound that inhibits the chronic progression of Parkinson's disease or protects dopamine neurons from disease etiology, thereby suppressing the progression of neurological dysfunction, so as to prolong the period of time until L-dopa is administered while also improving neuronal function; the quinolone compound of the invention is represented by Formula (1): wherein:


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