The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
Apr. 20, 2012
Alison Jo-anne Woolford, Cambridge, GB;
Steven Howard, Cambridge, GB;
Ildiko Maria Buck, Cambridge, GB;
Gianni Chessari, Cambridge, GB;
Christopher Norbert Johnson, Cambridge, GB;
Emiliano Tamanini, Cambridge, GB;
James Edward Harvey Day, Cambridge, GB;
Elisabetta Chiarparin, Cambridge, GB;
Thomas Daniel Heightman, Cambridge, GB;
Martyn Frederickson, Cambridge, GB;
Charlotte Mary Griffiths-jones, Cambridge, GB;
Alison Jo-Anne Woolford, Cambridge, GB;
Steven Howard, Cambridge, GB;
Ildiko Maria Buck, Cambridge, GB;
Gianni Chessari, Cambridge, GB;
Christopher Norbert Johnson, Cambridge, GB;
Emiliano Tamanini, Cambridge, GB;
James Edward Harvey Day, Cambridge, GB;
Elisabetta Chiarparin, Cambridge, GB;
Thomas Daniel Heightman, Cambridge, GB;
Martyn Frederickson, Cambridge, GB;
Charlotte Mary Griffiths-Jones, Cambridge, GB;
Astex Therapeutics Limited, Cambridge, GB;
Abstract
The invention relates to bicyclic heterocycle compounds of formula (I): or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R, R, R, R, R, R, R, R, R, R, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.