The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Feb. 13, 2013
Applicants:

Theodore Mark Kamenecka, Palm Beach Gardens, FL (US);

Rong Jiang, Fuquay Varina, NC (US);

Xinyi Song, Jupiter, FL (US);

Philip Lograsso, Jupiter, FL (US);

Michael Darin Cameron, Port Saint Lucie, FL (US);

Derek R. Duckett, Jupiter, FL (US);

Inventors:

Theodore Mark Kamenecka, Palm Beach Gardens, FL (US);

Rong Jiang, Fuquay Varina, NC (US);

Xinyi Song, Jupiter, FL (US);

Philip LoGrasso, Jupiter, FL (US);

Michael Darin Cameron, Port Saint Lucie, FL (US);

Derek R. Duckett, Jupiter, FL (US);

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/4196 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/4965 (2006.01); A61K 31/5377 (2006.01); C07D 239/42 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); C07D 491/10 (2006.01);
U.S. Cl.
CPC ...
C07D 239/42 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 491/10 (2013.01);
Abstract

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.


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