The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
May. 09, 2007
Applicants:
Paul Joseph Dyson, Ecublens, CH;
Wee Han Ang, Ecublens, CH;
Inventors:
Paul Joseph Dyson, Ecublens, CH;
Wee Han Ang, Ecublens, CH;
Assignee:
Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/00 (2006.01); A61K 31/28 (2006.01); A61K 31/555 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07F 15/0046 (2013.01); C07F 15/002 (2013.01); C07F 15/0033 (2013.01); C07F 15/0073 (2013.01);
Abstract
The present invention relates to organometallic compounds useful in the treatment of metastasis. The organometallic compounds comprise a ligand that is covalently bound to a bioactive compound, which is an inhibitor of a resistance pathway or a derivative thereof. Preferably, the organometallic compounds are half-sandwich ('piano-stool') compounds. The compounds of the present invention offer a high variability with respect to the bioactive compound and to the nature of the ligand bound to a central transition metal.