The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Sep. 20, 2007
Applicants:

Peter Kresten Nielsen, Holte, DK;

Frantisek Hubalek, Copenhagen Ø, DK;

Inger Lautrup-larsen, Virum, DK;

Svend Ludvigsen, Lynge, DK;

Ulla Ribel-madsen, Virum, DK;

Per Balschmidt, Hørsholm, DK;

Per Nørgaard, Humlebæk, DK;

Svend Havelund, Bagsværd, DK;

Inventors:

Peter Kresten Nielsen, Holte, DK;

Frantisek Hubalek, Copenhagen Ø, DK;

Inger Lautrup-Larsen, Virum, DK;

Svend Ludvigsen, Lynge, DK;

Ulla Ribel-Madsen, Virum, DK;

Per Balschmidt, Hørsholm, DK;

Per Nørgaard, Humlebæk, DK;

Svend Havelund, Bagsværd, DK;

Assignee:

Novo Nordisk A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); C07K 14/62 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.


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