The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
Nov. 27, 2012
National Yang Ming University, Taipei, TW;
Zee-Fen Chang, Taipei, TW;
Hsiao-Hui Lee, Taipei, TW;
National Yang Ming University, Taipei, TW;
Abstract
A set of agents is provided for probing/detecting the activation of Rho-associated protein kinase I and II individually encoding their amino acid sequence (SEQ ID NO:1 for ROCKI and SEQ ID NO:2 for ROCKII) in biological samples. The agents include one antibody to specifically recognize ROCKI Serphosphorylation and one antibody to specifically recognize ROCKII Serphosphorylation. The agents can be used for pathological analysis in cardiovascular diseases, cancer, neurological diseases or other diseases/disorders involving ROCKs and also for basic medical research. Moreover, the agents can be used for screening inhibitors against ROCKI and II.