The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Jun. 30, 2011
Applicants:

Soo-chang Song, Seoul, KR;

Jang IL Kim, Seongnam-si, KR;

Inventors:

Soo-Chang Song, Seoul, KR;

Jang Il Kim, Seongnam-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); B82Y 5/00 (2011.01); A61K 9/00 (2006.01); A61K 49/18 (2006.01); B82Y 15/00 (2011.01); C08G 79/02 (2006.01); C08L 85/02 (2006.01);
U.S. Cl.
CPC ...
B82Y 5/00 (2013.01); A61K 9/0009 (2013.01); A61K 49/1857 (2013.01); B82Y 15/00 (2013.01); C08G 79/025 (2013.01); C08L 85/02 (2013.01);
Abstract

The present invention relates to a poly(organophosphazene)-superparamagnetic nanoparticle complex including a biodegradable and thermosensitive poly(organophosphazene) and a iron oxide (FeO, Magnetite)-series ferrite superparamagnetic nanoparticle, a preparation method, and uses of carrying a physiologically-active material, a bio-material and a biomaterial for cancer hyperthermia. The iron oxide is used as a MRI contrast agent for Tand T* weighted image, and the poly(organophosphazene) shows a sol-to-gel behavior depending upon the temperature change. The complex is a bound-type where the superparamagnetic ferrite nanoparticle is bonded to phosphazene-based polymer via hydrophobic binding, and a mixed-type where the superparamagnetic ferrite nanoparticle is physically mixed with the phosphazene-based polymer.


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