The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Apr. 22, 2010
Applicants:

Hock Seng Tan, East Brunswick, NJ (US);

Siew Lian Chung, East Brunswick, NJ (US);

Inventors:

Hock Seng Tan, East Brunswick, NJ (US);

Siew Lian Chung, East Brunswick, NJ (US);

Assignee:

Bionex Pharmaceuticals LLC, North Brunswick, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61M 35/00 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01);
U.S. Cl.
CPC ...
A61M 35/00 (2013.01); A61K 9/0056 (2013.01); A61K 9/006 (2013.01); A61K 9/7007 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01);
Abstract

Provided is a dual-release, dual-adhesiveness flexible thin film dosage form comprising: a quick-release subfilm comprising an admixture of polymer, which comprises predominantly highly water-soluble polymer(s), and a bioactive agent, the polymers and other components of the quick-release subfilm adapted to provide 20 minutes or less erodibility for the quick-release subfilm; and laminated against the quick-release subfilm, a sustained-release subfilm comprising an admixture of polymer, which comprises predominantly hydrophilic, bioadhesive polymer(s), and a second bioactive agent, which can be the same as the first, the polymers and other components of the sustained-release subfilm adapted to provide erodibility of 1 hour or more and 20 hours or less for the sustained-release subfilm, the dosage form having a thickness of 30 mil or less, and being more adhesive on the sustained-release side.


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