The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
May. 13, 2013
Applicants:
Di Yu, Uppsala, SE;
Magnus Essand, Uppsala, SE;
Inventors:
Di Yu, Uppsala, SE;
Magnus Essand, Uppsala, SE;
Assignee:
Immunicum Aktiebolag, Gothenburg, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); A61K 48/00 (2006.01); A61K 35/76 (2006.01); A61K 45/06 (2006.01); A61K 38/16 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 48/0058 (2013.01); A61K 35/761 (2013.01); A61K 45/06 (2013.01); A61K 38/164 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C07K 2319/10 (2013.01); C12N 2710/10322 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10345 (2013.01); C12N 2810/6054 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention provides a hexon Tat-PTD modified adenovirus, a gene delivery vector based on the modified adenovirus that enhances gene delivery efficiency, and an oncolytic agent based on the modified adenovirus that enhances tumor cell killing efficiency and improves therapeutic outcome.