The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2015
Filed:
Oct. 09, 2009
Applicant:
Bret Berner, Half Moon Bay, CA (US);
Inventor:
Bret Berner, Half Moon Bay, CA (US);
Assignee:
Alvine Pharmaceuticals, Inc., San Carlos, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); C12N 9/50 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4873 (2013.01); A61K 9/1623 (2013.01); A61K 9/2013 (2013.01); A61K 9/2077 (2013.01); A61K 9/2095 (2013.01); A61K 9/4858 (2013.01); A61K 9/5042 (2013.01); A61K 9/5084 (2013.01); C12N 9/50 (2013.01);
Abstract
The therapeutic efficacy of zymogen proteins for oral administration is improved by including in the formulation one or more excipients that optimize pH and other reaction conditions for rapid activation of the zymogen shortly after ingestion.