The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Dec. 31, 2009
Applicants:
Patrick Y. LU, Rockville, MD (US);
David Evans, North Potomac, MD (US);
Jun John Xu, Germantown, MD (US);
Inventors:
Patrick Y. Lu, Rockville, MD (US);
David Evans, North Potomac, MD (US);
Jun John Xu, Germantown, MD (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12N 15/1136 (2013.01); C12N 15/1137 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/113 (2013.01); C12N 2310/17 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01);
Abstract
The present invention provides small interfering RNA (siRNA) molecules, compositions containing the molecules, and methods of using the molecules and compositions to treat breast cancer. In one aspect, a multi-targeted siRNAi cocktail is disclosed. The siRNA molecules may be encapsulated in nanoparticles to further enhance their anti-cancer activity. The compositions may also be used in combination with other anti-cancer agents, such as bevacizumab.