The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Jun. 29, 2010
Applicants:
Alexey G. Katrukha, Turku, FI;
Alexander B. Postnikov, Moscow, RU;
Tatiana I. Solovyeva, Nakhabino, RU;
Alexey V. Kharitonov, Moscow, RU;
Inventors:
Alexey G. Katrukha, Turku, FI;
Alexander B. Postnikov, Moscow, RU;
Tatiana I. Solovyeva, Nakhabino, RU;
Alexey V. Kharitonov, Moscow, RU;
Assignee:
Hytest Ltd., Turku, FI;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/22 (2006.01); G01N 33/574 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57407 (2013.01); C07K 16/18 (2013.01); C07K 2317/33 (2013.01); G01N 2333/475 (2013.01); G01N 2800/32 (2013.01);
Abstract
The present invention relates to a method for diagnosing a cardiovascular or cancer disease by detecting IGFBP-4 (Insulin-like Growth Factor Binding Protein-4) fragments in a patient sample. Antibodies specifically recognizing novel epitopes originated by enzyme-dependent cleavage of IGFBP-4 are also disclosed.