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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9012519 B1

PDFFull Text
Date of Patent:
Apr. 21, 2015

Filed:

Feb. 26, 2013

Compositions and methods of delivery of pharmacological agents

Applicant:

Abraxis Bioscience, Llc, Los Angeles, CA (US);

Inventors:

Neil P. Desai, Los Angeles, CA (US);

Patrick Soon-Shiong, Los Angeles, CA (US);

Vuong Trieu, Calabasas, CA (US);

Assignee:

Abraxis Bioscience, LLC, Los Angeles, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Marsha Tsay

Int. Cl.
CPC ...
A61K 47/42 (2006.01); A61K 9/14 (2006.01); A61K 9/51 (2006.01); C07K 14/76 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/19 (2006.01); A61K 31/05 (2006.01); A61K 31/16 (2006.01); A61K 31/337 (2006.01); A61K 47/18 (2006.01); B82Y 5/00 (2011.01); A61K 31/164 (2006.01); A61K 31/165 (2006.01); A61K 31/198 (2006.01); A61K 31/343 (2006.01); A61K 31/355 (2006.01); A61K 31/427 (2006.01); A61K 31/436 (2006.01); A61K 31/4745 (2006.01); A61K 31/7048 (2006.01); A61K 38/13 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/0019 (2013.01); A61K 9/0078 (2013.01); A61K 9/1075 (2013.01); A61K 9/146 (2013.01); A61K 9/19 (2013.01); A61K 31/05 (2013.01); A61K 31/16 (2013.01); A61K 31/337 (2013.01); A61K 47/18 (2013.01); B82Y 5/00 (2013.01); A61K 31/164 (2013.01); A61K 31/165 (2013.01); A61K 31/198 (2013.01); A61K 31/343 (2013.01); A61K 31/355 (2013.01); A61K 31/427 (2013.01); A61K 31/436 (2013.01); A61K 31/4745 (2013.01); A61K 31/7048 (2013.01); A61K 38/13 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01); Y10S 977/779 (2013.01); Y10S 977/911 (2013.01); Y10S 977/705 (2013.01);
Abstract

The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and/or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.

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