The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Oct. 11, 2011
Varsha Gupta, Encinitas, CA (US);
Joel Renick, San Diego, CA (US);
Graeme Freestone, San Diego, CA (US);
Alan P. Kaplan, San Diego, CA (US);
Varsha Gupta, Encinitas, CA (US);
Joel Renick, San Diego, CA (US);
Graeme Freestone, San Diego, CA (US);
Alan P. Kaplan, San Diego, CA (US);
Abstract
The invention provides a novel chemical series of formula I, as well as methods of use thereof for binding to the benzodiazepine site of the GABAreceptor and negatively modulating the α5 subtype of GABA, and use of the compound of formula I in the manufacture of a medicament for the treatment of GABAreceptor associated disorders. The invention further provides a method of modulation of one or more GABAsubtypes in an animal comprising administering to the animal an effective amount of a compound of formula (I).