The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2015

Filed:

Sep. 29, 2011
Applicants:

Bengt Leonard Åslund, Alderley Park, GB;

Carl-johan Aurell, Alderley Park, GB;

Martin Hans Bohlin, Alderley Park, GB;

Eric Thomas Healy, Waltham, MA (US);

David Richard Jensen, Waltham, MA (US);

David Thomas Jonaitis, Waltham, MA (US);

Stephan Parent, Waltham, MA (US);

Tesfai Sebhatu, Alderley Park, GB;

BO Ingvar Ymén, Alderley Park, GB;

Inventors:

Bengt Leonard Åslund, Alderley Park, GB;

Carl-Johan Aurell, Alderley Park, GB;

Martin Hans Bohlin, Alderley Park, GB;

Eric Thomas Healy, Waltham, MA (US);

David Richard Jensen, Waltham, MA (US);

David Thomas Jonaitis, Waltham, MA (US);

Stephan Parent, Waltham, MA (US);

Tesfai Sebhatu, Alderley Park, GB;

Bo Ingvar Ymén, Alderley Park, GB;

Assignees:

AstraZeneca AB, Sodertalje, SE;

Nektar Therapeutics, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); C07D 489/04 (2006.01); A61K 47/48 (2006.01); C07C 51/41 (2006.01); C07C 55/07 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); C07D 489/04 (2013.01); C07C 51/41 (2013.01); C07C 55/07 (2013.01); A61K 31/485 (2013.01);
Abstract

Naloxol-polyethlyene glycol conjugates of the formula: are provided in oxalate or phosphate salt forms including crystalline forms. Methods of preparing the salt forms and pharmaceutical compositions comprising the salt forms are also provided.


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