The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Jun. 11, 2010
Yoshikazu Nakamura, Tokyo, JP;
Ling Jin, Tokyo, JP;
Satoko Yamazaki, Tokyo, JP;
Hisako Ikeda, Tokyo, JP;
Masahiro Muraguchi, Osaka, JP;
Yoshikazu Nakamura, Tokyo, JP;
Ling Jin, Tokyo, JP;
Satoko Yamazaki, Tokyo, JP;
Hisako Ikeda, Tokyo, JP;
Masahiro Muraguchi, Osaka, JP;
Ribomic Inc., Tokyo, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
Provided are an aptamer bound to chymase to inhibit activity of chymase; an aptamer containing a nucleotide sequence represented by XGAUAGANNUAAXwherein Xand Xare the same or different and each is A or G, and Nand Nare the same or different and each is A, G, C, U or T; a complex containing the aptamer and a functional substance (e.g., affinity substance, labeling substance, enzyme, drug delivery medium, drug and the like); a pharmaceutical or a reagent containing the aptamer or complex; a detection and a purification methods of chymase using the aptamer or complex and the like.