The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Apr. 25, 2005
Olivier Civelli, Irvine, CA (US);
Rainer K. Reinscheid, Irvine, CA (US);
Yanling Xu, Irvine, CA (US);
Olivier Civelli, Irvine, CA (US);
Rainer K. Reinscheid, Irvine, CA (US);
Yanling Xu, Irvine, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Compositions and methods that act on Neuropeptide S receptors (NPSR) (also known as 'TGR23' or 'vasopressin receptor-related receptor 1 (VRR1)') to cause desired effects in the bodies of human or animal subjects. Neuropeptide S (NPS) and other agonists of the NPSR may be administered to cause arousal, awakening, alertness, spontaneous movement, bronchoconstriction, contraction of bronchial smooth muscle or other effects. Antagonists of the NPSR may be administered to cause decreased arousal, decreased awakening, decreased alertness, decreased spontaneous movement, sleep, somnolence, sedation, anxiolytic effects, normalized sleep patterns, normalized sleep stages, increased duration of sleep, bronchodilation, relaxation of broncheal smooth muscle or other effects.