The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2015

Filed:

Apr. 30, 2008
Applicants:

Isabel Haro Villar, Madrid, ES;

José M. Gomora Elena, Madrid, ES;

Luisa M Perez Rodríguez, Madrid, ES;

Raimon Sanmarti Sala, Barcelona, ES;

Inventors:

Isabel Haro Villar, Madrid, ES;

José M. Gomora Elena, Madrid, ES;

Luisa M Perez Rodríguez, Madrid, ES;

Raimon Sanmarti Sala, Barcelona, ES;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07K 7/64 (2006.01); G01N 33/566 (2006.01); G01N 33/564 (2006.01); C07K 14/75 (2006.01); C07K 14/78 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); A61K 38/00 (2013.01); C07K 14/75 (2013.01); C07K 14/78 (2013.01); C07K 2319/40 (2013.01); G01N 33/686 (2013.01); G01N 2800/102 (2013.01);
Abstract

The present invention concerns a chimeric polypeptide, capable of detecting the antibodies generated in rheumatoid arthritis, comprising at least two citrulinated peptide subunits: (i) one derived from the α or β chain of the fibrin and (ii) a second derived from the filaggrin. In addition, the invention comprises an antigenic composition, a method and a kit for the diagnosis of rheumatoid arthritis, from the detection of the autoantibodies generated during the course of said disease.


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