The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Sep. 16, 2009
Mark Mercola, La Jolla, CA (US);
Marcia Dawson, La Jolla, CA (US);
John Cashman, San Diego, CA (US);
Paul J. Bushway, San Diego, CA (US);
Mark Mercola, La Jolla, CA (US);
Marcia Dawson, La Jolla, CA (US);
John Cashman, San Diego, CA (US);
Paul J. Bushway, San Diego, CA (US);
Burnham Institute for Medical Research, La Jolla, CA (US);
Human Biomolecular Research Institute, San Diego, CA (US);
Abstract
Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof: Ris independently hydrogen or (C-C)alkyl; Ris independently hydrogen, (C-C)alkyl, aryl, or heteroaryl; Ris independently hydrogen, (C-C)alkyl, CFor CF; Ris independently (C-C)alkyl, aryl, 2-tetrahydrofurylmethyl, an aliphatic tertiary amine, or 4-methoxybenzyl; or Rand Rmay be joined together to form a 5 or 6 member ring lactone; Ris independently hydrogen, (C-C)alkyl, a 2- or 4-R-substituted aromatic ring selected from a 4-R-phenyl or a 2-R-5-pyridyl, aryl, heteroaryl, aliphatic tertiary amine or halogen; and R, R, R, R, R, R, are each independently hydrogen, (C-C)alkyl, aryl, optionally substituted phenyl, heteroaryl, a heterocyclic ring, an aliphatic tertiary amine, or halogen.