The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Dec. 08, 2009
Johannes Fruehauf, Newton, MA (US);
Moreshwar Bhanudas Vaze, Bedford, MA (US);
Floyd Stephen Laroux, Jr., Brookline, MA (US);
Noel Joy Sauer, Attleboro, MA (US);
Johannes Fruehauf, Newton, MA (US);
Moreshwar Bhanudas Vaze, Bedford, MA (US);
Floyd Stephen Laroux, Jr., Brookline, MA (US);
Noel Joy Sauer, Attleboro, MA (US);
Marina Biotech, Inc., Bothell, WA (US);
Abstract
Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium or BTP. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating viral diseases and disorders. The bacterium or BTP includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.