The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Aug. 05, 2011
Applicants:
Sohye Kang, Torrance, CA (US);
Rohini Deshpande, Camarillo, CA (US);
Rebecca E. Mccoy, Port Orchard, WA (US);
Leslie P. Miranda, Thousand Oaks, CA (US);
Arvia E. Morris, Seattle, WA (US);
Inventors:
Sohye Kang, Torrance, CA (US);
Rohini Deshpande, Camarillo, CA (US);
Rebecca E. McCoy, Port Orchard, WA (US);
Leslie P. Miranda, Thousand Oaks, CA (US);
Arvia E. Morris, Seattle, WA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); C07K 16/00 (2006.01); C07K 5/062 (2006.01); C07K 5/065 (2006.01); C07K 5/072 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 5/0606 (2013.01); C07K 5/06078 (2013.01); C07K 5/06104 (2013.01); C07K 2317/14 (2013.01); C12N 5/0037 (2013.01); C12N 2500/32 (2013.01); C12N 2500/46 (2013.01); C12N 2501/105 (2013.01); C12N 2501/998 (2013.01); C12N 2510/02 (2013.01);
Abstract
The present invention relates to the culture of animal cells in serum-free culture medium. The present invention provides particular dipeptides that can improve recombinant protein production and cell viability in such cultures, especially in the absence of peptones.