The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2015

Filed:

Dec. 23, 2011
Applicants:

SA Won Lee, Daejeon, KR;

DO Hoon Kim, Seoul, KR;

Bong OH Kim, Daejeon, KR;

Min Hyo Seo, Daejeon, KR;

Inventors:

Sa Won Lee, Daejeon, KR;

Do Hoon Kim, Seoul, KR;

Bong Oh Kim, Daejeon, KR;

Min Hyo Seo, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 47/34 (2006.01); A01N 25/28 (2006.01); A61K 9/16 (2006.01); A61K 31/175 (2006.01); A61K 31/27 (2006.01); A61K 31/436 (2006.01); A61K 31/485 (2006.01); A61K 31/519 (2006.01); A61K 31/565 (2006.01); A61K 31/57 (2006.01); A61K 31/554 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A01N 25/28 (2013.01); A61K 9/1694 (2013.01); A61K 9/1635 (2013.01); A61K 9/1647 (2013.01); A61K 31/175 (2013.01); A61K 31/27 (2013.01); A61K 31/436 (2013.01); A61K 31/485 (2013.01); A61K 31/519 (2013.01); A61K 31/565 (2013.01); A61K 31/57 (2013.01); A61K 31/554 (2013.01);
Abstract

A sustained-release microparticle containing a poorly water-soluble drug is disclosed. The sustained-release microparticle containing a poorly water-soluble drug has a multivalent metal ion salt of polylactic acid having at least one terminal carboxyl group or a derivative thereof. The poorly water-soluble drug is entrapped in the multivalent metal ion salt of polylactic acid or a derivative thereof The polylactic acid has at least one terminal carboxyl group or a derivative thereof has an average molecular weight number from 500 to 5,000 daltons. A method for preparing a sustained-release polymeric microparticles containing a poorly water-soluble drug is provided.


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