The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Jun. 30, 2008
George Y. Daniloff, Los Altos, CA (US);
Robert C. Spiro, Half Moon Bay, CA (US);
David M. Gravett, Mountain View, CA (US);
Patrick J. Hillas, San Francisco, CA (US);
Pingren He, Sunnyvale, CA (US);
George Y. Daniloff, Los Altos, CA (US);
Robert C. Spiro, Half Moon Bay, CA (US);
David M. Gravett, Mountain View, CA (US);
Patrick J. Hillas, San Francisco, CA (US);
Pingren He, Sunnyvale, CA (US);
Carbylan Therapeutics, Inc., Palo Alto, CA (US);
Abstract
The present application provides sterile hyaluronic polymer compositions than are useful, e.g., as medical devices, biomedical adhesives, and sealants. Generally, provided are sterile dry compositions comprising a thiol-derivatized hyaluronic acid and one or more stabilizing excipients. Also provided are related kits and methods. The compositions described herein are particularly robust to sterilizing irradiation, and substantially maintain both their molecular weight and gelation parameters such as gelation time after sterilization, such that such sterile compositions are capable of hydrogel formation.