The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2015

Filed:

May. 02, 2011
Applicants:

Hillary Overholser, Goshen, IN (US);

Jennifer Woodell-may, Warsaw, IN (US);

Inventors:

Hillary Overholser, Goshen, IN (US);

Jennifer Woodell-May, Warsaw, IN (US);

Assignee:

Biomet Biologics, LLC, Warsaw, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61L 24/10 (2006.01); A61K 35/14 (2006.01); A61L 24/00 (2006.01);
U.S. Cl.
CPC ...
A61L 24/108 (2013.01); A61K 35/14 (2013.01); A61L 24/0005 (2013.01); A61K 38/4833 (2013.01);
Abstract

Methods, apparatus, and compositions related to generating and using thrombin. Methods include preparing a solution comprising thrombin by precipitating fibrinogen from a liquid comprising whole blood or a blood fraction. Precipitated fibrinogen is removed from the liquid to form a post-precipitation liquid that is incubated with calcium and a plurality of beads to form a clot. A solution comprising thrombin is separated from the clot. Thrombin prepared thereby can be used as a tissue sealant and in methods of applying a tissue sealant to subject, including application of an autologous tissue sealant.


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