The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Sep. 15, 2014
University of Ottawa, Ottawa, CA;
Jeffrey Keillor, Ottawa, CA;
Karine Caron, Braddon, AU;
University of Ottawa, Ottawa, CA;
Abstract
Novel fluorescent markers of Formula I: are disclosed herein, wherein X and Y are independently or together absent or are independently selected from R and Rare independently selected from H and alkyl; Ar is phenyl or heteroaryl; L is absent or a spacer selected from the group consisting of —NH—; —(CH)NH—; —NHSO—; —(CH)NHCO—; -(cycloalkyl)NHCO—; —(CH)NHSO—; -(cycloalkyl)NHSO—; —CONH(CH)NHCO—; —CONH(cycloalkyl)NHCO—; —NHCO(CH)NHCO—; —NHCO(cycloalkyl)NHCO—; —(CH)SONH—; -(cycloalkyl)SONH—; —(CH)NHCSNH—; -(cycloalkyl)NHCSNH—; —CR═CR—; —C≡C—; —(CH)N═CH—; -(cycloalkyl)N═CH—; —N═CH(CH)—; —N═CH(cycloalkyl)-; n is an integer ranging from 1 to 5; F is a fluorophore selected from the group consisting of fluorescein, rhodamine, eosin, thionine, safranin, coumarin, methoxycoumarin, dansyl, BODIPY and BODIPY derivatives; and wherein X, Y and L may be positioned in a 1,3,5; 1,2,3; 1,3,4 or in a 3,4,5 configuration respectively.