The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Aug. 27, 2012
Mukund Keshav Gurjar, Pune, IN;
Neelakandan Kaliaperumal, Pune, IN;
Pravin Prabhakar Ahirrao, Pune, IN;
Raghuramireddy Baireddy, Pune, IN;
Prabhakaran Balasubramanian, Pune, IN;
Srinivas Nandala, Pune, IN;
Prasad Pandurang Panchabhai, Pune, IN;
Samit Satish Mehta, Pune, IN;
Mukund Keshav Gurjar, Pune, IN;
Neelakandan Kaliaperumal, Pune, IN;
Pravin Prabhakar Ahirrao, Pune, IN;
Raghuramireddy Baireddy, Pune, IN;
Prabhakaran Balasubramanian, Pune, IN;
Srinivas Nandala, Pune, IN;
Prasad Pandurang Panchabhai, Pune, IN;
Samit Satish Mehta, Pune, IN;
Abstract
The present invention provides a convenient and industrially viable process for preparation of Zolmitriptan (I) having desired purity. The invention specifically relates to a method for isolating (S)-4-(4-hydrazinobenzyl)-1,3-oxazolidin-2-one hydrochloride (IIIa) of desired purity by separating the undesired inorganic side products such as stannous hydroxide by manipulation of pH at different stages and finally treating with N,N-dimethylamino butyraldehyde diethyl acetal in an acidic medium to provide Zolmitriptan (I) conforming to regulatory specifications.