The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
May. 09, 2014
Applicant:
Brandeis University, Waltham, MA (US);
Inventor:
Li Deng, Newton Lower Falls, MA (US);
Assignee:
Brandeis University, Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 453/04 (2006.01); C07C 67/313 (2006.01); C07C 253/30 (2006.01); C07D 207/327 (2006.01);
U.S. Cl.
CPC ...
C07D 453/04 (2013.01); C07C 67/313 (2013.01); C07C 253/30 (2013.01); C07D 207/327 (2013.01);
Abstract
One aspect of the present invention relates to quinine-based and quinidine-based catalysts. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral electron-deficient alkene, comprising the step of: reacting a prochiral electron-deficient alkene with a nucleophile in the presence of a catalyst; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized quinine or quinidine.