The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Apr. 06, 2012
Applicants:
Xiaoguang Lei, Beijing, CN;
Xiuguo Zhang, Beijing, CN;
Inventors:
Xiaoguang Lei, Beijing, CN;
Xiuguo Zhang, Beijing, CN;
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01); A61K 31/475 (2006.01); A61K 31/4745 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); A61K 31/4745 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/4866 (2013.01);
Abstract
Disclosed are novel camptothecin derivatives having anti-tumor activity (the basic structure thereof is as shown in the figure) and compositions of such compounds and use thereof. The compounds according to the present invention exhibit very good water solubility and stability, show good selectivity among drugs of the same category, and have a very high therapeutic index. Such compounds are promising as therapeutic agents for treating tumors.