The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Mar. 04, 2014
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Mingyue Zhou, Hayward, CA (US);
Wenyan Shen, Thousand Oaks, CA (US);
Bei Shan, Redwood City, CA (US);
Margrit Schwarz, San Carlos, CA (US);
David Park Meininger, Seattle, WA (US);
Tom Boone, Newbury Park, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12P 21/02 (2006.01); C12N 9/10 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); A61K 47/48369 (2013.01); C12Y 203/01043 (2013.01);
Abstract
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.