The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Mar. 26, 2004
Applicants:

Sudhir Paul, Missouri City, TX (US);

Yasuhiro Nishiyama, Houston, TX (US);

Inventors:

Sudhir Paul, Missouri City, TX (US);

Yasuhiro Nishiyama, Houston, TX (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 47/48 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48238 (2013.01); A61K 2039/505 (2013.01); A61K 2039/60 (2013.01); A61K 2039/6093 (2013.01); C07K 14/005 (2013.01); C07K 16/1063 (2013.01); C07K 2316/96 (2013.01); C07K 2317/34 (2013.01); C12N 2740/16122 (2013.01);
Abstract

A covalently reactive ligand analogue (CAL) of formula (1): wherein, L. . . L. . . Lare components defining a ligand determinant, Lis a component unit of the ligand determinant selected from the group consisting of an amino acid residue, sugar residue, a fatty acid residue and a nucleotide, L' is a functional group of L, Y″ is atom, covalent bond or linker, Y′ is an optional charged or neutral group Y is a covalently reactive electrophilic group that reacts specifically with a receptor that binds to said ligand determinant, and n is an integer from 1 to 1000 m is an integer from 1 to 30.


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