The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Feb. 07, 2013
Applicant:

Glenmark Pharmaceuticals S.a., La Chaux-de-Fonds, CH;

Inventors:

Laxmikant Atmaram Gharat, Maharashtra, IN;

Abhisek Banerjee, Howrah, IN;

Neelima Khairatkar-Joshi, Maharashtra, IN;

Vidya Ganapati Kattige, Maharashtra, IN;

Assignee:

Glenmark Pharmaceuticals S.A., La Chaux-de-Fonds, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/517 (2006.01); C07D 239/88 (2006.01); C07D 215/233 (2006.01); C07D 239/94 (2006.01); C07D 401/12 (2006.01); C07D 217/22 (2006.01); C07D 217/24 (2006.01);
U.S. Cl.
CPC ...
C07D 239/88 (2013.01); C07D 215/233 (2013.01); C07D 239/94 (2013.01); C07D 401/12 (2013.01); C07D 217/22 (2013.01); C07D 217/24 (2013.01);
Abstract

The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.


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