The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Sep. 22, 2009
Applicants:
Hsing-pang Hsieh, Miaoli County, TW;
Selvaraj Mohane Coumar, Pondicherry, IN;
Yu-sheng Chao, Monmouth Junction, NJ (US);
Inventors:
Hsing-Pang Hsieh, Miaoli County, TW;
Selvaraj Mohane Coumar, Pondicherry, IN;
Yu-Sheng Chao, Monmouth Junction, NJ (US);
Assignee:
National Health Research Institutes, Miaoli County, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/94 (2006.01); C07D 413/12 (2006.01); C07D 403/12 (2006.01); C07D 411/12 (2006.01); A61K 31/4365 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); C07D 401/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C12N 9/99 (2006.01); C07D 498/04 (2006.01); C07D 215/20 (2006.01); C07D 215/26 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); C07D 491/04 (2006.01); C07D 495/14 (2006.01); C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4365 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); C07D 239/94 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/04 (2013.01); C07D 495/04 (2013.01); C07D 495/14 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C12N 9/99 (2013.01);
Abstract
Fused multicyclic compounds of formula (I): wherein R', R″, X, Y, Z, A, B, C, D, and n are defined herein. Also disclosed are a method for inhibiting protein kinase (e.g., Aurora kinase) activity and a method for treating a protein kinase mediated disorder (e.g., cancer) with these compounds.