The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Feb. 14, 2013
Applicants:

Kai Gerlach, Mittelbiberach, DE;

Christian Eickmeier, Mittelbiberach, DE;

Claudia Heine, Biberach an der Riss, DE;

Niklas Heine, Biberach an der Riss, DE;

Alexander Weber, Biberach an der Riss, DE;

Inventors:

Kai Gerlach, Mittelbiberach, DE;

Christian Eickmeier, Mittelbiberach, DE;

Claudia Heine, Biberach an der Riss, DE;

Niklas Heine, Biberach an der Riss, DE;

Alexander Weber, Biberach an der Riss, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 475/12 (2006.01); C07D 475/00 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 498/22 (2006.01); C07D 487/14 (2006.01); C07D 471/14 (2006.01); C07D 498/14 (2006.01);
U.S. Cl.
CPC ...
C07D 475/00 (2013.01); C07D 487/14 (2013.01); C07D 471/14 (2013.01); C07D 498/14 (2013.01); C07D 475/12 (2013.01);
Abstract

The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Aβ peptides.


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