The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Jan. 14, 2010
Applicants:

Guillermo Garcia-cardena, Cambridge, MA (US);

Peter Mack, Chapel Hill, NC (US);

Jeffrey T. Borenstein, Newton, MA (US);

Ahmad S. Khalil, Brookline, MA (US);

Eli J. Weinberg, Needham, MA (US);

Jason O. Fiering, Boston, MA (US);

Ernest S. Kim, Cambridge, MA (US);

William J. Adams, Jr., Cambridge, MA (US);

Inventors:

Guillermo Garcia-Cardena, Cambridge, MA (US);

Peter Mack, Chapel Hill, NC (US);

Jeffrey T. Borenstein, Newton, MA (US);

Ahmad S. Khalil, Brookline, MA (US);

Eli J. Weinberg, Needham, MA (US);

Jason O. Fiering, Boston, MA (US);

Ernest S. Kim, Cambridge, MA (US);

William J. Adams, Jr., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C40B 30/06 (2006.01); C40B 60/12 (2006.01); C12M 1/32 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12M 23/12 (2013.01); C12M 35/04 (2013.01);
Abstract

A high-throughput flow system includes an array of wells and a separate mechanical tip positioned within each well. Each mechanical tip is separately actuated to impart a shear stress pattern. A separate sleeve may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable within its corresponding sleeve. Alternatively, a separate post may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable about its corresponding post.


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