The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Jul. 12, 2013
Applicant:
Oxford Immunotec Limited, Oxfordshire, GB;
Inventors:
Ajit Lalvani, Oxford, GB;
Ansar Pathan, Oxford, GB;
Assignee:
Oxford Immunotec Limited, Oxfordshire, GB;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/531 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); C07K 14/35 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 14/35 (2013.01); G01N 33/5695 (2013.01); Y10S 435/975 (2013.01);
Abstract
A method of diagnosing in a host infection by or exposure to a mycobacterium which expresses ESAT-6 comprising (i) contacting a population of T cells from the host with one or more peptides or analogues selected from the peptides represented by SEQ ID NO:1 to 11 and analogues thereof which can bind a T cell receptor which recognises any of the said peptides, and (ii) determining whether the T cells of said T cell population recognise the peptide(s) and/or analogue(s). The method may performed in vivo. Peptides and a kit which enable the method to be carried out are provided.