The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Dec. 15, 2006
Applicants:

Burkhard Schlutermann, Au, DE;

Manfred Kohlmeyer, Basel, CH;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/138 (2006.01); A61K 9/20 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5078 (2013.01); A61K 9/2081 (2013.01);
Abstract

A pharmaceutical pellet is provided, comprising a spherical core containing the active substance with a smooth surface and a coating on the core, which controls pH-independent release of the active substance. With a pellet of this kind, the release of the active substance may follow a profile with a lag-phase from 60 minutes to 840 minutes, where during the lag-phase a proportion of 5 wt. % or less of the active substance is released. Furthermore, the active substance may be released from the pellet with a profile such that, after the lag-phase, the release of the active substance is between 3 and 25 wt. % per hour. The active substance is a metoprolol salt.


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