The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Apr. 08, 2010
Applicants:

Alexander Berthold Hendrik Bakker, Hillegom, NL;

Willem Egbert Marissen, Woerden, NL;

Robert Arjen Kramer, Utrecht, NL;

Cornelis Adriaan DE Kruif, De Bilt, NL;

Inventors:
Assignee:

Crucell Holland B.V., Leiden, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 31/14 (2006.01); C07K 16/10 (2006.01); C07K 14/005 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 14/005 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C12N 2760/20122 (2013.01); G01N 33/56983 (2013.01);
Abstract

Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.


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