The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Jul. 03, 2014
Applicant:
Crucell Holland B.v., Leiden, NL;
Inventors:
Ronald Vogels, Linschoten, NL;
Theodorus H. J. Kwaks, Voorschoten, NL;
Assignee:
Crucell Holland B.V., Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 39/395 (2006.01); A61K 39/42 (2006.01); A61K 39/38 (2006.01); A61K 39/145 (2006.01); C12Q 1/70 (2006.01); C07K 16/10 (2006.01); A61K 47/48 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1018 (2013.01); A61K 39/42 (2013.01); A61K 47/4853 (2013.01); G01N 33/56983 (2013.01);
Abstract
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses. These binding molecules do not bind to hemagglutinin of influenza A viruses. Further provided are nucleic acid molecules encoding the binding molecules, and compositions comprising the binding molecules. The binding molecules can be used in the diagnosis of, prophylaxis against, and/or treatment of influenza B virus infections.