The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2015

Filed:

Mar. 07, 2008
Applicants:

Naoko Hamasaki, Tokyo, JP;

Shoichi Ide, Tokyo, JP;

Inventors:

Naoko Hamasaki, Tokyo, JP;

Shoichi Ide, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 65/10 (2006.01); B01D 69/02 (2006.01); B22F 9/24 (2006.01); B01J 13/00 (2006.01); B01D 69/08 (2006.01); G01N 15/08 (2006.01);
U.S. Cl.
CPC ...
B22F 9/24 (2013.01); B01D 69/08 (2013.01); B01D 65/10 (2013.01); B01D 65/102 (2013.01); B01J 13/0043 (2013.01); B22F 2998/00 (2013.01); G01N 2015/084 (2013.01);
Abstract

The present invention provides a method of testing the integrity of a microporous membrane using a colloid solution containing metal particles or metal compound particles that can accurately determine the integrity of a virus removal membrane formed of hydrophilized synthetic polymer that has been subjected to protein solution filtration, and to provide a method of producing the colloid solution. The colloid solution comprises a solvent and metal particles dispersed in the solvent, and the solvent comprises components (A) and (B), (A) and (C), or (A), (B), and (C), wherein the component (A) is an anionic polymer having a sulfonic acid group, the component (B) is at least one nonionic surfactant selected from the group consisting of a nonionic surfactant having a polycyclic structure in a hydrophobic moiety and a polyoxyethylene sorbitan fatty acid ester, and the component (C) is a water-soluble polymer having a pyrrolidone group.


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