The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2015
Filed:
Oct. 01, 2008
Gregory J. Sommer, Livermore, CA (US);
Anson V. Hatch, Tracy, CA (US);
Ying-chih Wang, Pleasanton, CA (US);
Anup K. Singh, Danville, CA (US);
Gregory J. Sommer, Livermore, CA (US);
Anson V. Hatch, Tracy, CA (US);
Ying-Chih Wang, Pleasanton, CA (US);
Anup K. Singh, Danville, CA (US);
Sandia Corporation, Albuquerque, NM (US);
Abstract
Embodiments of the present invention provide devices, systems, and methods for microscale isoelectric fractionation. Analytes in a sample may be isolated according to their isoelectric point within a fractionation microchannel. A microfluidic device according to an embodiment of the invention includes a substrate at least partially defining a fractionation microchannel. The fractionation microchannel has at least one cross-sectional dimension equal to or less than 1 mm. A plurality of membranes of different pHs are disposed in the microchannel. Analytes having an isoelectric point between the pH of the membranes may be collected in a region of the fractionation channel between the first and second membranes through isoelectric fractionation.