The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Feb. 01, 2012
Applicants:

Takashi Sawada, Shizuoka, JP;

Tomohiro Danjo, Shizuoka, JP;

Keiichi Motosawa, Shizuoka, JP;

Takayuki Furuta, Yokohama, JP;

Maki Ichioka, Shizuoka, JP;

Masamori Sugawara, Mishima, JP;

Noriaki Uesaka, Shizuoka, JP;

Inventors:

Takashi Sawada, Shizuoka, JP;

Tomohiro Danjo, Shizuoka, JP;

Keiichi Motosawa, Shizuoka, JP;

Takayuki Furuta, Yokohama, JP;

Maki Ichioka, Shizuoka, JP;

Masamori Sugawara, Mishima, JP;

Noriaki Uesaka, Shizuoka, JP;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 235/02 (2006.01); C07D 471/04 (2006.01); A61K 31/4184 (2006.01); A61K 31/42 (2006.01); A61K 31/4355 (2006.01); A61K 31/4439 (2006.01); A61K 31/4525 (2006.01); A61K 31/497 (2006.01); A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4184 (2013.01); A61K 31/42 (2013.01); A61K 31/4355 (2013.01); A61K 31/4439 (2013.01); A61K 31/4525 (2013.01); A61K 31/497 (2013.01); A61K 31/519 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

A ring-fused heterocyclic derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof having a T-type calcium channel regulatory effect and useful as a pruritus therapeutic and/or preventive agent, and the like are provided. In the general formula (I), Rrepresents optionally substituted lower alkyl, and the like; Rrepresents an optionally substituted cycloalkyl, and the like; Q represents a hydrogen atom, and the like; Rrepresents —C(═O)NRR(wherein Rand Rmay be the same or different, and each represents a hydrogen atom, and the like), and the like; Lrepresents —CRR— (wherein Rand Rmay be the same or different, and each represents a hydrogen atom, and the like), and the like; and Wand Wmay be the same or different, and each represents C—R(wherein Rrepresents a hydrogen atom, and the like), and the like.


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