The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Oct. 14, 2005
Elfrida R. Benjamin, Englishtown, NJ (US);
Zhengming Chen, Belle Meade, NJ (US);
Deyou Sha, Yardley, PA (US);
Laykea Tafesse, Robbinsville, NJ (US);
Samuel F. Victory, Oak Ridge, NC (US);
John W. F. Whitehead, Newtown, PA (US);
Elfrida R. Benjamin, Englishtown, NJ (US);
Zhengming Chen, Belle Meade, NJ (US);
Deyou Sha, Yardley, PA (US);
Laykea Tafesse, Robbinsville, NJ (US);
Samuel F. Victory, Oak Ridge, NC (US);
John W. F. Whitehead, Newtown, PA (US);
Purdue Pharma L.P., Stamford, CT (US);
Abstract
The invention relates to piperidinyl compounds of Formula (I): or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R-Rand Z are defined as set forth in the specification. The invention is also directed to an assay useful for identifying such compounds as N-type calcium channel modulators or blockers. The invention is also directed to the compounds of Formula (I) and compounds identified by the above assay, and the use of such compounds to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.