The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Mar. 11, 2013
Applicants:
Jan Paul Medema, Amsterdam, NL;
Hans Van Eenennaam, Oss, NL;
Marco Guadagnoli, Amsterdam, NL;
Fiona Clare Kimberley, Amsterdam, NL;
Uyen Truong Phan, Palo Alto, CA (US);
Inventors:
Jan Paul Medema, Amsterdam, NL;
Hans Van Eenennaam, Oss, NL;
Marco Guadagnoli, Amsterdam, NL;
Fiona Clare Kimberley, Amsterdam, NL;
Uyen Truong Phan, Palo Alto, CA (US);
Assignee:
Bionovion Holding B.V., Oss, NL;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); G01N 33/53 (2006.01); C07K 16/28 (2006.01); C07K 16/24 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C07K 16/2875 (2013.01); C07K 16/241 (2013.01); G01N 33/6863 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C07K 2317/34 (2013.01);
Abstract
The present invention relates to a binding compound which binds to human APRIL. More specifically the invention provides, compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition of cell proliferation and cancer.