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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9000022 B1

PDFFull Text
Date of Patent:
Apr. 07, 2015

Filed:

Jul. 25, 2013

Imidazole based lxr modulators

Applicant:

Exelixis Patent Company Llc, South San Francisco, CA (US);

Inventors:

Brett B. Busch, San Diego, CA (US);

Brenton T. Flatt, Poway, CA (US);

Xiao-Hui Gu, Potomac, MD (US);

Shao Po Lu, San Diego, CA (US);

Richard Martin, San Diego, CA (US);

Raju Mohan, Encinitas, CA (US);

Michael Charles Nyman, San Diego, CA (US);

Edwin J. Schweiger, San Diego, CA (US);

William C. Stevens, Jr., La Jolla, CA (US);

Tie-Lin Wang, San Diego, CA (US);

Yinong Xie, San Diego, CA (US);

Assignee:

Exelixis Patent Company LLC, South San Francisco, CA (US);

Attorneys:

Fox Rothschild LLP

Gerard P. Norton

Robert N. Henrie, II

Primary Examiner:

Kamal A Saeed

Assistant Examiner:

Janet L Coppins

Int. Cl.
CPC ...
A61K 31/4174 (2006.01); C07D 233/64 (2006.01); C07D 401/04 (2006.01); C07D 409/04 (2006.01); C07D 233/90 (2006.01); C07D 401/10 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 405/10 (2006.01); C07D 409/10 (2006.01); C07D 409/14 (2006.01); C07D 417/10 (2006.01); C07D 231/12 (2006.01); C07D 231/22 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 233/64 (2013.01); C07D 401/04 (2013.01); C07D 409/04 (2013.01); C07D 233/90 (2013.01); C07D 401/10 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 405/10 (2013.01); C07D 409/10 (2013.01); C07D 409/14 (2013.01); C07D 417/10 (2013.01); C07D 231/12 (2013.01); C07D 231/22 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 487/08 (2013.01);
Abstract

Methods of using compounds of the invention, such as compounds of Formulae IIa, IIb, IIc, or IId and pharmaceutically acceptable salts thereof are disclosed. The compounds are useful in treating, preventing, inhibiting or ameliorating the symptoms of a disease or disorder that is modulated or otherwise affected by nuclear receptor activity, or in which nuclear receptor activity is implicated.

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