The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Mar. 18, 2011
Applicants:

Abdelouahid Samadi, Madrid, ES;

José Luis Marco Contelles, Madrid, ES;

Irene Bolea Tomás, Barcelona, ES;

Francisco Javier Luque Garriga, Barcelona, ES;

Mercedes Unzeta López, Barcelona, ES;

Inventors:

Abdelouahid Samadi, Madrid, ES;

José Luis Marco Contelles, Madrid, ES;

Irene Bolea Tomás, Barcelona, ES;

Francisco Javier Luque Garriga, Barcelona, ES;

Mercedes Unzeta López, Barcelona, ES;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 403/12 (2006.01); A61K 31/496 (2006.01); A61K 31/445 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 403/12 (2013.01);
Abstract

The present invention relates to a compound of formula (I): wherein: Rand Rare selected from among H and C1-C10 alkyl; Ris selected from among H, —OR, N, —CN, —C(O)R, —C(O)OR, —C(O)NRR, —C═NR, —OC(O)R, —NRR, —NRC(O)R, —NO, —N═CRR, halogen and C1-C10 alkyl, wherein Rand Rare selected from among H, alkyl, alkenyl, cycloalkyl and aryl; X, Y, Z, Zand Zare selected independently from among CH and N; A is selected from among (CH), NH, O and CO, wherein n is an integer between 1 and 6, to the procedure for the obtainment of said compounds, to a pharmaceutical composition comprising said compound, and to the use thereof in the treatment of a neurodegenerative disease, more particularly treatment of Alzheimer's or Parkinson's disease.


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