The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Jun. 22, 2011
Yongqi Deng, Newton, MA (US);
Liang Zhu, Waltham, MA (US);
Gerald W. Shipps, Jr., Stoneham, MA (US);
Sie-mun Lo, Revere, MA (US);
Binyuan Sun, Chestnut Hill, MA (US);
Xiaohua Huang, Malden, MA (US);
Corey Bienstock, Natick, MA (US);
Alan B. Cooper, West Caldwell, NJ (US);
Xiaolei Gao, Bridgewater, NJ (US);
Xin Yao, Scotch Plains, NJ (US);
Hugh Y. Zhu, Warren, NJ (US);
Joseph M. Kelly, Parlin, NJ (US);
Sobhana Babu Boga, Scotch Plains, NJ (US);
Abdul-basit Alhassan, Scotch Plains, NJ (US);
Jayaram R. Tagat, Westfield, NJ (US);
Umar Faruk Mansoor, Framingham, MA (US);
Kevin J. Wilson, Newton, MA (US);
Brendan M. O'boyle, Boston, MA (US);
Matthew Hersh Daniels, Cambridge, MA (US);
Adam Schell, Newton, MA (US);
Phieng Siliphaivanh, Newton, MA (US);
Christian Fischer, Natick, MA (US);
Yongqi Deng, Newton, MA (US);
Liang Zhu, Waltham, MA (US);
Gerald W. Shipps, Jr., Stoneham, MA (US);
Sie-Mun Lo, Revere, MA (US);
Binyuan Sun, Chestnut Hill, MA (US);
Xiaohua Huang, Malden, MA (US);
Corey Bienstock, Natick, MA (US);
Alan B. Cooper, West Caldwell, NJ (US);
Xiaolei Gao, Bridgewater, NJ (US);
Xin Yao, Scotch Plains, NJ (US);
Hugh Y. Zhu, Warren, NJ (US);
Joseph M. Kelly, Parlin, NJ (US);
Sobhana Babu Boga, Scotch Plains, NJ (US);
Abdul-Basit Alhassan, Scotch Plains, NJ (US);
Jayaram R. Tagat, Westfield, NJ (US);
Umar Faruk Mansoor, Framingham, MA (US);
Kevin J. Wilson, Newton, MA (US);
Brendan M. O'Boyle, Boston, MA (US);
Matthew Hersh Daniels, Cambridge, MA (US);
Adam Schell, Newton, MA (US);
Phieng Siliphaivanh, Newton, MA (US);
Christian Fischer, Natick, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.