The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Jan. 19, 2009
Applicants:

Philippe Olivier Belmont, Lyons, FR;

Laurent Meijer, Roscoff, FR;

Philip Cohen, Dundee, GB;

Amaury Patin, Villeurbanne, FR;

Johann Bosson, Etrembières, FR;

Peter Gregory Goekjian, Lyons, FR;

Inventors:

Philippe Olivier Belmont, Lyons, FR;

Laurent Meijer, Roscoff, FR;

Philip Cohen, Dundee, GB;

Amaury Patin, Villeurbanne, FR;

Johann Bosson, Etrembières, FR;

Peter Gregory Goekjian, Lyons, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/18 (2006.01); C07F 7/10 (2006.01); A61K 31/695 (2006.01); A61K 31/473 (2006.01); C07D 219/04 (2006.01); C07D 215/14 (2006.01); C07D 215/20 (2006.01); C07D 219/06 (2006.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
C07D 219/04 (2013.01); C07D 215/14 (2013.01); C07D 215/20 (2013.01); C07D 219/06 (2013.01); C07F 7/0812 (2013.01);
Abstract

The invention relates to kinase inhibitors of the formula (I) in which —Rto R═H; ether or polyether, amino; NO; NH-carbamate; NH—CO—R, with R such as defined above; Nand derivatives thereof of the 1,2,3-triazole type; —R=—OH; halogen; —OR with R such as defined above; OH-carbamate; OH-carbonate; NH, NH-carbamate; NH—CO—R, with R such as defined above; Nand derivatives thereof of the 1,2,3-triazole type; N(R,R); —R'═H or a C1-C12 alkyl, —R═H; R; (R or R′)—Si, with R such as defined above; optionally substituted aryl, heteroaryl; halogen (iodine); alkynyl; —Rand R═H, C-Calkyl; —Rand R═H, R (or R′) such as defined above. These compounds can be used as kinase inhibitors in particular for treating cancer.


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