The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8999934 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 07, 2015

Filed:

Aug. 09, 2010
Applicants:

Isaiah Fidler, Houston, TX (US);

Sun-jin Kim, Houston, TX (US);

Inventors:

Isaiah Fidler, Houston, TX (US);

Sun-jin Kim, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/337 (2006.01); A01K 67/027 (2006.01); A61K 31/4188 (2006.01); C12N 5/079 (2010.01); C12N 5/09 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/337 (2013.01); A01K 67/027 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A61K 31/4188 (2013.01); A61K 31/506 (2013.01); C12N 5/0622 (2013.01); C12N 5/0693 (2013.01); C12N 2502/08 (2013.01); C12N 2502/30 (2013.01); G01N 33/5008 (2013.01);
Abstract

The disclosure relates to an endothelin receptor antagonist for use in the prevention or treatment of brain metastases in combination with a cytotoxic chemotherapy agent, radiotherapy or both. The endothelin receptor antagonist may for example be bosentan, macitentan or a mixture of bosentan and macitentan.


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Fidler, Isaiah. (2015). Treatment of astrocytes-tumor cells inhibitors of endothelin receptors (U.S. Patent No. 8999934). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8999934

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