The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Jan. 05, 2007
Applicants:

Wolfgang Neuberger, F.T. Labuan, MY;

Volker Albrecht, Jena, DE;

Danilo Castro, Montevideo, UY;

Inventors:

Wolfgang Neuberger, F.T. Labuan, MY;

Volker Albrecht, Jena, DE;

Danilo Castro, Montevideo, UY;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 8/65 (2006.01); A61K 8/49 (2006.01); A61K 31/407 (2006.01); A61K 31/555 (2006.01); A61L 27/24 (2006.01); A61L 27/54 (2006.01); A61Q 19/06 (2006.01); A61Q 19/08 (2006.01); A61K 41/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 8/65 (2013.01); A61K 9/1271 (2013.01); A61K 8/4946 (2013.01); A61K 31/407 (2013.01); A61K 31/555 (2013.01); A61L 27/24 (2013.01); A61L 27/54 (2013.01); A61Q 19/06 (2013.01); A61Q 19/08 (2013.01); A61K 41/0071 (2013.01); A61K 2800/434 (2013.01); A61K 2800/81 (2013.01); A61L 2300/414 (2013.01); A61L 2300/604 (2013.01);
Abstract

Innovative non-surgical methods and compositions are provided for administering PDT to promote tissue regeneration or augmentation while minimizing scarring and risk of infection. Among several areas of application, is the treatment of acute and chronic wounds which have afflicted epidermal and connective tissue layers of the body. Another application area is as cosmetic surgery/treatments, including: reducing wrinkles, sulcus, scars (acne or traumatic caused), sequelae cellulite, as well as for other skin irregularities, to give a smoother skin surface. This invention consists of a collagen based or other suitable biodegradable supporting matrix which is embedded with a liposomal loaded photosensitizer. In one embodiment of this invention a liposomal formulated photosensitizer is first injected at the site followed by collagen implantation and PDT treatment. In another embodiment a liposomal formulated photosensitizer is incorporated in the collagen. Generally 30 minutes after collagen is mixed with photosensitizer the light activation is done. The matrix may also carry important growth factors and cytokines, which promote fibroblast cell migration and proliferation, to the wound site. Microbial infection at the wound site can also be controlled by antibacterial PDT.


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