The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Feb. 15, 2013
Rqx Pharmaceuticals, Inc., La Jolla, CA (US);
Robert I. Higuchi, Solana Beach, CA (US);
Tucker Curran Roberts, San Diego, CA (US);
Peter Andrew Smith, La Jolla, CA (US);
David Campbell, San Diego, CA (US);
Prasuna Paraselli, San Diego, CA (US);
RQX Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.